B.1.429—加州病毒
B.1.526—紐約病毒
B.1.1.7+E484—英國病毒最新變種SARS-CoV-2=中國不可分割必須扛起責任的禍亂全世界武漢肺炎病毒 501Y.V2 variant =南非變種
P.1 variant=巴西變種
1 All three variants have the N501Y mutation, which changes the amino acid asparagine (N) to tyrosine (Y) at position 501 in the receptor-binding domain of the spike protein.
The 501Y.V2 and P.1 variants both have two additional receptor-binding–domain mutations, K417N/T and E484K. These mutations increase the binding affinity of the receptor-binding domain to the angiotensin-converting enzyme 2 (ACE2) receptor
Sinovarc怕乳滑所以不敢寫
COVID-19 疫苗會激起宿主產生SRAR-CoV-2-specific的CD4+和CD8+的T-cell反應以及產生中和性的抗體(neutralizing antibodies),提供宿主保護性的免疫力。
目前的COVID-19 mRNA疫苗,激起宿主產生的抗體,已經證實減少對SARS-CoV-2變異株的中和性的活性,而T-cell免疫反應,可能在抵抗SARS-CoV-2的變異株的宿主保護作用扮演角色。
(源自SARS-CoV-2 mutations,vaccines,and immunity:implication of variants of concer Signal transduction and targeted therapy 203(2021) published 22 May 2021)